Acute lymphocytic leukemia (ALL), also known as acute lymphoblastic leukemia, is a type of cancer that affects the blood and bone marrow. It starts from young white blood cells called lymphocytes in the bone marrow; mainly characterized by an overproduction of immature white blood cells, called lymphoblasts or leukemic blasts. ALL are caused by a lack of normal circulating blood cells. The exact causes of ALL remain largely unknown, but it is thought to result from mutations in one or more of the genes that normally control blood cell development. This mutation will result in abnormal growth.
ALL is diagnosed by examining samples of blood and bone marrow in a variety of tests such as full blood count, bone marrow examination, cytogenetic tests, molecular tests, and others. The characteristics of ALL differ greatly between children and adults. These days with treatment, the majority of children with ALL can be cured of their disease; in adults, cure rates are more variable.
The type of treatment used will depend on several factors, including the sub-type of ALL, the genetic make-up of the leukemic cells, age, and general health. The main treatment options include chemotherapy, targeted therapy, immunotherapy, surgery, radiation therapy, and stem cell transplant.
Over the last few years, the treatment paradigm of ALL has changed due to the launch of a number of therapies that have improved treatment outcomes for patients with ALL such as Blincyto and Besponsa; and the first chimeric antigen receptor (CAR) T-cells for relapsed/refractory pediatric and young adult ALL patients, namely Kymriah. However, chemotherapies are highly effective and remain the backbone of frontline ALL treatment.
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The Acute Lymphocytic Leukemia (ALL) market report also covers emerging drugs, current treatment practices, Acute Lymphocytic Leukemia (ALL) market share of the individual therapies, current and forecasted Acute Lymphocytic Leukemia (ALL) Market Size from 2017 to 2030 segmented by seven major markets.
The report provides a detailed current Acute Lymphocytic Leukemia (ALL) treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.
Acute Lymphocytic Leukemia (ALL) Market Key Facts
The Market Size of Acute Lymphocytic Leukemia (ALL) in the 7MM was USD 1,246 million (in 2017).
The total incident cases of Acute Lymphocytic Leukemia (ALL) in the 7MM were observed to be 10,341 in 2017, which are expected to grow during the study period (2017–2030).
Among the 7MM, the US accounted for the highest number of cases of ALL, i.e. 5,816 cases in 2017.
Among the European-5 countries, Germany had the highest incident population of ALL, followed by France and the UK. On the other hand, Spain had the lowest incident cases of ALL, in 2017.
Key Benefits of Acute Lymphocytic Leukemia (ALL) Market Report
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Acute Lymphocytic Leukemia (ALL) market report provides an in-depth analysis of Acute Lymphocytic Leukemia (ALL) Market Size, Share, Trend, Epidemiology and Market Forecast till 2030, in 7 major market i.e. EU5 (Germany, Italy, Spain, France and the UK), Japan, and the United States.
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The Acute Lymphocytic Leukemia (ALL) market report will help in developing business strategies by understanding the Acute Lymphocytic Leukemia (ALL) Market trends & developments, key players and future market competition that will shape and drive the Acute Lymphocytic Leukemia (ALL) market in the upcoming years.
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The Acute Lymphocytic Leukemia (ALL) market report covers Acute Lymphocytic Leukemia (ALL) current treatment practices, emerging drugs, market share of the individual therapies in 7 MM.
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The report provides a detailed assessment of the Acute Lymphocytic Leukemia (ALL) market in terms of market drivers & barriers, Unmet Needs, market opportunities, patient population, comparative analysis of pipeline products with detailed clinical profiles, and other factors.
Acute Lymphocytic Leukemia (ALL) Market
The ALL market size is anticipated to increase for the study period, 2017–2030. Growth of ALL markets is expected to be driven by rising incident cases of ALL, expected more steadily uptake of approved therapies mainly CAR T-cell therapies and emerging as well and expected increase in investment in the R&D activities.
The Acute Lymphocytic Leukemia (ALL) market outlook section of the report helps to build the detailed comprehension of the historic, current and forecasted Acute Lymphocytic Leukemia (ALL) market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand for better technology.
The report gives a thorough detail of Acute Lymphocytic Leukemia (ALL) market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, and view of the key opinion leaders.
Acute Lymphocytic Leukemia (ALL) Epidemiology
The Acute Lymphocytic Leukemia (ALL) epidemiology section covers insights about historical and current Acute Lymphocytic Leukemia (ALL) patient pool and forecasted trends for every seven major countries (i.e. the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan from 2017 to 2030.
It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Acute Lymphocytic Leukemia (ALL) Drugs Uptake and Key Market Players
The Acute Lymphocytic Leukemia (ALL) Drugs Uptake section focuses on the rate of uptake of the potential drugs recently launched in the Acute Lymphocytic Leukemia (ALL) market or expected to get launched in the market during the study period. The analysis covers Acute Lymphocytic Leukemia (ALL) market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
At present, several companies have indulged themselves to initiate clinical trials that investigate new treatment options or studying how to use existing treatment options better. The current developmental pipeline for ALL is very robust. The dynamics of the ALL market is anticipated to change in the coming years owing to the improvement in the rise in the number of healthcare spending across the world, increasing awareness and expected increase in investment in the R&D activities.
Some of the key players in the Acute Lymphocytic Leukemia (ALL) market includes:
Pharmacyclics
Incyte Corporation
Bristol-Myers Squibb
Roche
Novartis Pharmaceuticals
Janssen Research & Development
Servier
BioLineRx
Sanofi
Jazz Pharmaceuticals
Gilead Sciences
and others
Drugs Covered
Imbruvica (Ibrutinib)
Venetoclax
PBCAR0191
JZP-458
Lisocabtagene Maraleucel
Jakafi (ruxolitinib)
Motixafortide (BL-8040)
TC-110
UCART19
NiCord (omidubicel)
Eliquis (apixaban)
Isatuximab
And many others.
Table of Content
1. Key Insights
2. Executive Summary
3. Acute Lymphocytic Leukemia (ALL) Competitive Intelligence Analysis
4. Acute Lymphocytic Leukemia (ALL) Market Overview at a Glance
5. Acute Lymphocytic Leukemia (ALL) Disease Background and Overview
6. Acute Lymphocytic Leukemia (ALL) Patient Journey
7. Acute Lymphocytic Leukemia (ALL) Epidemiology and Patient Population
8. Acute Lymphocytic Leukemia (ALL) Treatment Algorithm, Current Treatment, and Medical Practices
9. Acute Lymphocytic Leukemia (ALL) Unmet Needs
10. Key Endpoints of Acute Lymphocytic Leukemia (ALL) Treatment
11. Acute Lymphocytic Leukemia (ALL) Marketed Products
12. Acute Lymphocytic Leukemia (ALL) Emerging Therapies
13. Acute Lymphocytic Leukemia (ALL) Seven Major Market Analysis
14. Attribute Analysis
15. Acute Lymphocytic Leukemia (ALL) Market Outlook (7 major markets)
16. Acute Lymphocytic Leukemia (ALL) Access and Reimbursement Overview
17. KOL Views on the Acute Lymphocytic Leukemia (ALL) Market.
18. Acute Lymphocytic Leukemia (ALL) Market Drivers
19. Acute Lymphocytic Leukemia (ALL) Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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Acute lymphocytic leukemia (ALL) Pipeline Insights, 2020
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