New York, July 01, 2019 Creative Biolabs, a leading biotech company with years of experiences, offers TCR Design, Construction, Generation and Optimization services to satisfy versatile needs from global clients of TCR engineered t cell development.
As a complex of integral membrane proteins, the T cell receptor (TCR) plays a significant role in activating T cells in response to the presentation of antigen and TCR engineered t cells are proved as a feasible and therapeutic potential tool that enhances the successful engraftment of T cells in tumors for the treatment of cancer.
With the support of the advanced TCR T technology platform and a professional team, scientists in Creative Biolabs can create tumor-specific T cells by identifying the candidate target tumor antigen and the sequence of tumor-specific TCR, in which the appropriate target sequence is introduced to modify T cells to target a wide variety of tumors with a higher specificity.
For TCR Design & Construction services, Creative Biolabs optimizes the conventional method that clones TCR genes into retroviral vectors and use them to transfer antigen specificity into other cells by combining the general steps into a single process to expedite TCR vector production. Compared to the traditional three-step process, that is, cloning whole TCR genes, producing a TCR expression cassette, and constructing a retroviral construct, TCR Design & Construction services in Creative Biolabs streamlines the TCR vector production process and can tailor the design and construction of TCR products.
“Our TCR engineering services cover each step of manufacturing and delivery pipeline, such as transgene expression, TCR/CD3 stability, lymphocyte antigen reactivity and cytotoxicity, animal experiments, etc., In Creative Biolabs, technicians can generate high-quality TCRs from patient’s TIL, phage display, in vivo system for TCR Generation & Optimization. We also provide cGMP-compliant TCR products for preclinical and clinical trials.” Introduced by a scientist in Creative Biolabs.
In addition, TCR biomarker identification & selection, TCR gene packaging & delivery, TCR in vitro assay, TCR-T preclinical in vivo test and TCR clinical trial are also available in Creative Biolabs. More information can be found at https://www.creative-biolabs.com/car-t/.
As a global company, Creative Biolabs has more than 200 talented and well-trained scientists located in different continents working closely with partners from the entire world to develop and produce medicines of tomorrow. Specifically, the established leading experts in TCR and CAR-T&NK cell immune therapy development offer the one-stop custom services that cover the entire new drug development pipeline, and an exclusive line of ready-to-use TCR and CAR-T&NK cell construction products, such as virus packaging, purification, expansion and titer determination kits. Furthermore, a unique unparalleled CAR construction and production platform has been built up for all four CAR generations.
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States